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Circulation: Cardiovascular Interventions

Clairol did the opposite of what most marketers would do: They didn’t want every woman on the street running around saying they were using their product. They wanted women to understand that their product was so good that people wouldn’t be able to tell if they were using it or not.

Sometimes, simply conveying how and why your product works is enough for consumers. Showing becomes more effective than telling.

Source: BBC News

In 1999, AdAge declared De Beers' "A Diamond is Forever" the most memorable slogan of the twentieth century. But the campaign, which proposed (pun very much intended) the idea that no marriage would be complete without a diamond ring, wasn't just riding on the coattails of an existing industry. De Beers actually built the industry ; it presented the idea that a diamond ring was a necessary luxury.

According to the New York Times , N.W. Ayer's game plan was to "create a situation where almost every person pledging marriage feels compelled to acquire a diamond engagement ring."

Advertisingcan make a relatively inexpensive product seem luxurious and essential.

Source: Coloribus

The very first part of Old Spice's "The Man Your Man Could Smell Like" campaign, created by Wieden + Kennedy and launched in February 2010, was the following commercial. It became a viral success practically overnight:

That video has over 51 million views as of this writing. Several months later, in June 2010, Old Spice followed up with a second commercial featuring the same actor, Isaiah Mustafa. Mustafa quickly became "Old Spice Guy," a nickname Wieden + Kennedy capitalized on with an interactive video campaign in which Mustafa responded to fans' comments on Facebook, Twitter, and other social media websites with short, personalized videos.

In about two days, the company had churned out 186 personalized, scripted, and quite funny video responses featuring Mustafa responding to fans online. According to Inc , these videos saw almost 11 million views, and Old Spice gained about 29,000 Facebook fans and 58,000 new Twitter followers.

"We were creating and sending miniature TV commercials back to individual consumers that were personalized, and we were doing it on a rapid-fire basis," Jason Bagley, creative director at Wieden + Kennedy and a writer for the campaign, told Inc . "No one expects to ask a question and then be responded to. I think that's where we broke through."

If you find your campaign's gained momentum with your fans and followers, do everything you can to keep them engaged while keeping your messaging true to your brand's voice and image.

Source: AdSoft Direct

To overcome the above problems, ESC Guidelines on pacing 294 —in patients with LVEF >35%—recommend a strategy of EPS followed by ILR if the EPS findings are unremarkable. With this strategy, a pacemaker was implanted in approximately half of the patients and these patients had syncope recurrence after pacemaker implantation in 0–7% of cases 188 , 217 . This strategy was safe; however, this Task Force recognizes that in the ‘real world’, an empirical pacemaker may be acceptable in selected patients at high risk of traumatic recurrence (e.g. elderly patients with unpredictable syncopes) and that an individual risk–benefit evaluation is warranted ( Figure 14 ).

Figure 14
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Therapeutic algorithm for patients presenting with unexplained syncope and bundle branch block. BBB = bundle branch block; CRT-D = cardiac resynchronization therapy defibrillator; EPS = electrophysiological study; ICD = implantable cardioverter defibrillator; ILR = implantable loop recorder; PM = pacemaker.

Figure 14
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Therapeutic algorithm for patients presenting with unexplained syncope and bundle branch block. BBB = bundle branch block; CRT-D = cardiac resynchronization therapy defibrillator; EPS = electrophysiological study; ICD = implantable cardioverter defibrillator; ILR = implantable loop recorder; PM = pacemaker.

Even if the quality of evidence is moderate, there is strong consensus that in patients with bifascicular BBB with a positive EPS or documentation of paroxysmal AV block during prolonged ECG monitoring, cardiac pacing is highly effective in preventing syncope recurrence. The evidence of efficacy of empirical pacing strategy is weak and the estimate of benefit is uncertain.

Although syncope is not associated with an increased incidence of sudden death in patients with preserved cardiac function, a high incidence of total deaths (about one-third sudden) was observed in patients with BBB and heart failure, previous myocardial infarction, or low ejection fraction. 345–347 Indeed, the high total and sudden mortality seems to be mainly related to underlying structural heart disease and ventricular tachyarrhythmias. In this latter situation, syncope is a risk factor, rather than the cause, of death. 218 Unfortunately, ventricular programmed stimulation does not seem to identify these patients correctly, and the finding of inducible ventricular arrhythmia (VA) should therefore be interpreted with caution. 345 , 346 Therefore, an implantable cardioverter defibrillator (ICD) or a cardiac resynchronization therapy defibrillator is indicated in patients with BBB, congestive heart failure, or previous myocardial infarction and depressed systolic function for the prevention of SCD, but may be unable to prevent the recurrence of syncope, which is often due to non-arrhythmic causes such as OH or vasodepressor reflex. The strategy for the management of patients with unexplained syncope and BBB is summarized in Figure 14 .

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